Although knowing that tigers reside in the mountain, one still insists on walking up there.

解释 ( paraphrase )
明明知道山上有老虎，却偏要向有老虎的山上走去。
这条谚语有两种意思。第一种：越是困难和艰险的地方，越是要去。表现了无所畏惧的精神。（含褒义）第二种是：明明知道前面有危险，却偏要冒险去干。（含贬义）

This proverb has two meanings: The more difficult and dangerous the place is, the more one wants to go there. It indicates a spirit of fearing nothing. Or it can mean that one knows well the dangers but insists on taking the risk away.

造句 ( example )
只有具备了“明知山有虎，偏向虎山行”的胆识，才能昂首阔步于成功的大道之上。